The single most common message we get from Portfolio-tier users is: 'I have 3,000 domains and I don't know which ones I should drop this year.' There's no right answer, but there's a right process.
The three buckets
Auto-renew (< 1% chance of drop regret), hand-review (unclear signal), and default-drop (no signal in 3+ years). Sort your portfolio into these three buckets 90 days before your renewal cliff and the decision gets much easier.